Charlie GOSSE
Institut Curie, Paris
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Biography
"After an initial formation at the Chemistry Department of the Ecole Normale Supérieure (Paris), I collaborated with the Physics Department during my PhD, working on the development of magnetic tweezers and on the synthesis of oligonucleotide-made nanostructures. DNA biophysics was still at the heart of my two post-doctoral stays, at Keio University (Yokohama) and Institut Curie (Paris). Then, I entered the Laboratory for Photonics and Nanostructures (Marcoussis), shifting my activities towards microdevice fabrication and analytical sciences. Later, I also devised there several perturbative approaches to study the dynamics of reaction networks, at the molecular as well as at the cellular scale."
Dynatwist by scDNA
Dynatwist is a supercoilable double-stranded DNA molecules with exceptional stability and high purity (> 95%).
Get fast, non-toxic, eco friendly and cost-effective DNA extraction with:
DNAbsolute - A column-free DNA extraction buffer
Ensure prolonged, stable blinking for microscopy with:
Everspark - A long-lasting buffer for dSTORM
Benefit from many other researchers innovations
Several publications
Kostrz D, Wayment-Steele HK, Wang JL, Follenfant M, Pande VS, Strick TR, Gosse C. A modular DNA scaffold to study protein-protein interactions at single-molecule resolution. Nat Nanotechnol. 2019 Oct;14(10):988-993. https://www.nature.com/articles/s41565-019-0542-7Mazari E, Zhao X, Migeotte I, Collignon J, Gosse C, Perea-Gomez A. A microdevice to locally electroporate embryos with high efficiency and reduced cell damage. Development. 2014 Jun;141(11):2349-59. https://dev.biologists.org/content/141/11/2349
Hoffmann C, Mazari E, Lallet-Millet S, Le Borgne R, Marchi V, Gosse C, Gueroui Z. Spatiotemporal control of microtubule nucleation and growth triggered by magnetic nanoparticle assembly. Nat. Nanotechnol. 2013 8 199-205. https://www.nature.com/articles/nnano.2012.246
Zrelli K, Barilero T, Cavatore E, Berthoumieux H, Le Saux T, Croquette V, Lemarchand A, Gosse C, Jullien L. Temperature modulation and quadrature detection for selective titration of two-state exchanging reactants. Anal Chem. 2011 Apr 1;83(7):2476-84 https://pubs.acs.org/doi/abs/10.1021/ac1026034
Barilero T, Le Saux T, Gosse C, Jullien L. Fluorescent thermometers for dual-emission-wavelength measurements: molecular engineering and application to thermal imaging in a microsystem. Anal Chem. 2009 Oct 1;81(19):7988-8000. https://pubs.acs.org/doi/abs/10.1021/ac901027f
Estévez-Torres A, Le Saux T, Gosse C, Lemarchand A, Bourdoncle A, Jullien L. Fourier transform to analyse reaction-diffusion dynamics in a microsystem. Lab Chip. 2008 Jul;8(7):1205-9. https://pubs.rsc.org/en/content/articlelanding/2008/lc/b805412f#!divAbstract
Bourdoncle A, Estévez Torres A, Gosse C, Lacroix L, Vekhoff P, Le Saux T, Jullien L, Mergny JL. Quadruplex-based molecular beacons as tunable DNA probes. J Am Chem Soc. 2006 Aug 30;128(34):11094-105. https://pubs.acs.org/doi/abs/10.1021/ja0608040
Koenig A, Hébraud P, Gosse C, Dreyfus R, Baudry J, Bertrand E, Bibette J. Magnetic force probe for nanoscale biomolecules. Phys Rev Lett. 2005 Sep 16;95(12):128301. https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.95.128301
Gosse C, Croquette V. Magnetic tweezers: micromanipulation and force measurement at the molecular level. Biophys J. 2002 Jun;82(6):3314-29. https://www.cell.com/biophysj/fulltext/S0006-3495(02)75672-5