Engineering simplicity in molecular biology  

Jean-Luc Evrard   

IBMP, Strasbourg, France

Who is Jean-Luc Evrard ?

Jean-Luc Evrard is a seasoned research engineer at the Institut de Biologie Moléculaire des Plantes (IBMP) in Strasbourg, France. With a background in molecular biology and bioinformatics, he has dedicated his career to developing practical solutions that streamline laboratory workflows. As the head of the Information Systems platform at IBMP, Evrard has been instrumental in implementing innovative technologies that enhance data management and experimental efficiency. One of these innovations was named EasYeast.

    The bottleneck behind the breakthrough

The idea behind EasYeast was born directly at the bench, during Jean-Luc’s own experiments with yeast two-hybrid screening, a technique that requires extracting plasmids from large numbers of yeast clones in parallel. As the screens grew, so did the workload: DNA extraction quickly became the bottleneck, slowing down the entire workflow. Existing protocols were time-consuming, used hazardous chemicals, and were poorly suited for high-throughput processing.

Jean-Luc set himself a challenge: create a method free from any bead-based lysis or toxic compounds, that would simplify yeast DNA extraction and eliminate the usual frustrations of traditional protocols.

EasYeast: Streamlining Yeast DNA extraction

After extensive optimization, EasYeast was born. Based solely on liquid solutions, this protocol checks all the boxes:

  • Speed & scalability: Scale up as needed and complete DNA extraction in minutes.
  • Safety: No use of toxic reagents.
  • Simplicity: Minimal steps, reducing the potential for error.
  • Versatility: Extract both plasmid and genomic DNA for PCR amplification or bacterial transformation.

By integrating EasYeast into their workflows, laboratories can enhance productivity and focus more on data analysis and interpretation.

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Empowering research through practical innovation  

Jean-Luc Evrard's commitment to improving laboratory practices is evident in his development of EasYeast. By addressing a common bottleneck in molecular biology, he has provided researchers with a tool that not only saves time but also improves the reliability of experimental results.

Ready to simplify your yeast extractions?