Odoo • Image et Texte

Pierre BON


"To infinity, and beyond!"


I am a researcher at CNRS at the University of Bordeaux (LP2N Lab) with a PhD in physics (Aix-Marseille University).
I develop new optical systems for microscopy, especially applied to biology.

Research topics

I have been developing optical microscopy tools since my Master student graduation. I am fascinated by playing with the light to maximize the knowledge we can get from a sample. I am currently working in the field of super-resolution imaging assisted by robust interferometry.

Fields of interest

Microscopy & imaging; light-matter interaction




The phase-only diffraction grating designed for optimal super-resolution PSF sampling. Phimask allows 3D localization deep in tissue with a quasi-isotropic precision and limited photon loss (<20%).

Several publications

Linarès-Loyez J, Ferreira JS, Rossier O, Lounis B, Giannone G, Groc L, Cognet L and Bon P. Self-Interference (SELFI) Microscopy for Live Super-Resolution Imaging and Single Particle Tracking in 3D. Front Phys. 2019 May;7:68. https://www.frontiersin.org/articles/10.3389/fphy.2019.00068/full

Kellermayer B, Ferreira JS, Dupuis J, Levet F, Grillo-Bosch D, Bard L, Linarès-Loyez J, Bouchet D, Choquet D, Rusakov DA, Bon P, Sibarita JB, Cognet L, Sainlos M, Carvalho AL, Groc L. Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses. Neuron. 2018 Oct 10;100(1):106-119.e7. https://www.cell.com/neuron/fulltext/S0896-6273(18)30785-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627318307852%3Fshowall%3Dtrue

Khadir S, Bon P, Vignaud D, Galopin E, McEvoy N, McCloskey D, Monneret S, Baffou. Optical Imaging and Characterization of Graphene and Other 2D Materials Using Quantitative Phase Microscopy. ACS Photonics. 2017 Sep, 4(12):3130-3139. https://pubs.acs.org/doi/10.1021/acsphotonics.7b00845

Aknoun S, Bon P, Savatier J, Wattellier B, Monneret S. Quantitative retardance imaging of biological samples using quadriwave lateral shearing interferometry. Opt Express. 2015 Jun 15;23(12):16383-406. https://pubs.acs.org/doi/10.1021/acsphotonics.7b00845

Aknoun S, Savatier J, Bon P, Galland F, Abdeladim L, Wattellier B, Monneret S. Living cell dry mass measurement using quantitative phase imaging with quadriwave lateral shearing interferometry: an accuracy and sensitivity discussion. J Biomed Opt. 2015;20(12):126009. https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-20/issue-12/126009/Living-cell-dry-mass-measurement-using-quantitative-phase-imaging-with/10.1117/1.JBO.20.12.126009.full?SSO=1

Bon P, Bourg N, Lécart S, Monneret S, Fort E, Wenger J, Lévêque-Fort S. Three-dimensional nanometre localization of nanoparticles to enhance super-resolution microscopy. Nat Commun. 2015 Jul 27;6:7764. https://www.nature.com/articles/ncomms8764

Bourg N, Mayet C, Dupuis G, Barroca T, Bon P, Lécart S, Fort E, Lévêque-Fort S. Direct optical nanoscopy with axially localized detection. Nature Photonics. 2015 Sep ; 9(9) :587-593. https://arxiv.org/pdf/1410.1563.pdf

Bon P, Lécart S, Fort E, Lévêque-Fort S. Fast label-free cytoskeletal network imaging in living mammalian cells. Biophys J. 2014 Apr 15;106(8):1588-95. https://www.sciencedirect.com/science/article/pii/S000634951400229X

Baffou G, Bon P, Savatier J, Polleux J, Zhu M, Merlin M, Rigneault H, Monneret S. Thermal imaging of nanostructures by quantitative optical phase analysis. ACS Nano. 2012 Mar 27;6(3):2452-8.  https://pubs.acs.org/doi/10.1021/nn2047586

Berto P, Bermúdez Ureña E, Bon P, Quidant R, Rigneault H, Baffou G. Quantitative absorption spectroscopy of nano-objects. Phys. Rev. B. 2012 Oct; 86(16):165417. https://journals.aps.org/prb/abstract/10.1103/PhysRevB.86.165417