Biography
After completing an engineering degree at the ESPCI Paristech in 2001 I carried out my Ph.D at the Pierre & Marie Curie University in Paris in Material Science. My early research work on single cell microfluidics was performed both in the laboratory for Photonics and Nanostructure (LPN-CNRS) in Marcoussis and in the lab of Steve Quake at Caltech. I joined the CNRS in 2004 as a tenured scientist, first at the ESPCI Neurobiology lab in Paris and later (2009) at the IINS (Interdisciplinary Institute for Neuroscience) in Bordeaux. I have expertise in microengineering and microscopy for biology. I am also a co-founder of Alvéole, a company commercializing a biomolecule printer invented in my lab.Research Topics
With my teammates, I try to improve exciting (for geek engineers) technologies at the crossroad of material science, microfabrication, optics and make them available for biologists. I aim at going a bit further than engineering proof of concepts. Adressing biological questions (mostly in neuroscience) with the tools we develop and also participating in their industrialization is a significant part of my research activity.Fields of interest
Bioengineering, Microscopy, Microfluidics, Neuroscience.
Technologies
Microfabrication, Optical Engineering, Programming, bread makingApplications
Drug Discovery, Live Cell Imaging, Mechanobiology
Stencell
Designed with Pierre-Olivier Strale and Aurélien Pasturel
Stencell is the ready-to-use sticky foil with compartments that you can use for cellular
confinement. It is designed to standardize the experiments and to
minimize the consumption of reagents.
Several publications
Studer V, Pepin A, Chen Y. Nanoembossing of thermoplastic polymers for microfluidic applications. Applied Physics Letters. 2002. 80: 3614-3616. doi: 10.1063/1.1479202Hong JW, Studer V, Hang G, Anderson WF, Quake SR. A nanoliter-scale nucleic acid processor with parallel architecture. Nat Biotechnol. 2004 Apr;22(4):435-9. doi: 10.1038/nbt951. Epub 2004 Mar 14. PMID: 15024389.
Studer V, Pepin A, Chen Y, Ajdari A. An integrated AC electrokinetic pump in a microfluidic loop for fast and tunable flow control. Analyst. 2004 Oct;129(10):944-9. doi: 10.1039/b408382m. Epub 2004 Aug 9. PMID: 15457328.
Bartolo D, Degré G, Nghe P, Studer V. Microfluidic stickers. Lab Chip. 2008 Feb;8(2):274-9. doi: 10.1039/b712368j. Epub 2007 Nov 22. PMID: 18231666.
Studer V, Bobin J, Chahid M, Mousavi HS, Candes E, Dahan M. Compressive fluorescence microscopy for biological and hyperspectral imaging. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):E1679-87. doi: 10.1073/pnas.1119511109. Epub 2012 Jun 11. PMID: 22689950; PMCID: PMC3387031.
Dupin I, Dahan M, Studer V. Investigating axonal guidance with microdevice-based approaches. J Neurosci. 2013 Nov 6;33(45):17647-55. doi:10.1523/JNEUROSCI.3277-13.2013. PMID: 24198357; PMCID: PMC6618420.
Dupin I, Lokmane L, Dahan M, Garel S, Studer V. Subrepellent doses of Slit1promote Netrin-1 chemotactic responses in subsets of axons. Neural Dev. 2015 Mar 20;10:5. doi: 10.1186/s13064-015-0036-8. PMID: 25888985; PMCID: PMC4373007.
Galland R, Grenci G, Aravind A, Viasnoff V, Studer V, Sibarita JB. 3D high-and super-resolution imaging using single-objective SPIM. Nat Methods. 2015 Jul;12(7):641-4. doi: 10.1038/nmeth.3402. Epub 2015 May 11. PMID: 25961414.
Strale PO, Azioune A, Bugnicourt G, Lecomte Y, Chahid M, Studer V. Multiprotein Printing by Light-Induced Molecular Adsorption. Adv Mater. 2016 Mar 9;28(10):2024-9. doi: 10.1002/adma.201504154. Epub 2015 Dec 21. PMID: 26689426.
Pasturel A, Strale PO, Studer V. Tailoring Common Hydrogels into 3D Cell Culture Templates. Adv Healthc Mater. 2020 Aug 2:e2000519. doi:10.1002/adhm.202000519. Epub ahead of print. PMID: 32743980.